CHROMSYSTEMS

Multilevel Whole Blood Calibrator Set
6PLUS1

The 6PLUS1 Multilevel Whole Blood Calibrator Set is designed for use with MassTox® Immunosuppressants in Whole Blood by LC-MS/MS. These lyophilized calibrators, based on human whole blood, are essential for calibrating measurement methods in clinical diagnostics. They are used for the quantitative determination of immunosuppressants such as cyclosporin A, tacrolimus, sirolimus, and everolimus in whole blood. The set ensures accurate and reliable results, following FDA recommendations, for the precise monitoring of immunosuppressant drug levels in patient blood samples.

Malondialdehyde HPLC Test
Malondialdehyde in Serum/Plasma – HPLC

Chromsystems’ Malondialdehyde in Serum/Plasma – HPLC kit quantifies malondialdehyde (MDA), a biomarker of lipid peroxidation and oxidative stress. Used in evaluating patients with respiratory or degenerative conditions, it provides interference-free analysis for reliable results.

HPLC Vitamin C Test
Vitamin C in Plasma/Serum – HPLC

Chromsystems’ HPLC test enables precise quantification of Vitamin C in plasma or serum. Featuring enhanced column and sample stability, it helps assess nutritional status or deficiency-related conditions like scurvy or oxidative stress.

Urine Control
MassCheck Amino Acid Analysis Urine Controls

The MassCheck Amino Acid Analysis Urine Controls are designed to ensure the accuracy and reliability of amino acid quantification in urine samples via LC-MS/MS. Available in three distinct concentration levels, these lyophilized controls are based on a human matrix, providing a realistic standard for method validation and routine quality assurance. They are essential for laboratories engaged in metabolic disorder diagnostics, offering confidence in analytical results and aiding in the maintenance of stringent quality standards.

Cortisol & Cortisone Saliva Control
6PLUS1 Multilevel Saliva Calibrator Set

The 6PLUS1 Multilevel Saliva Calibrator Set is specifically designed for the accurate quantification of cortisol and cortisone levels in saliva samples using LC-MS/MS. This calibrator set comprises six distinct concentration levels, facilitating the creation of precise calibration curves essential for reliable hormone analysis. Utilizing a human-based matrix, these calibrators closely mimic actual patient samples, thereby enhancing the accuracy and traceability of results.

CONTROL SÉRICO DE Β-CAROTENO
β-Carotene in Serum/Plasma

El kit HPLC de β-caroteno está diseñado para la cuantificación precisa de los niveles de β-caroteno en muestras de suero y plasma. Utiliza un proceso optimizado de preparación de muestras que combina precipitación y extracción rápidas.

Antibiotics Assay
Antibiotics in Serum/Plasma – HPLC

Chromsystems’ Antibiotics in Serum/Plasma is an in vitro diagnostic assay for the quantitative determination of ampicillin, cefepime, ceftazidime, linezolid, meropenem and piperacillin in human serum and plasma samples for monitoring patients’ blood levels of these antibiotics. The HPLC determination with subsequent UV detection is done in two groups, the first run via a mobile phase gradient, the second run isocratically. Two internal standards and stable matrix products ensure precise quantification while the additionally included priming solution increases sample stability notably.

Cortisol/Cortisone Saliva Controls
MassCheck Chromsystems Saliva Controls

The MassCheck Chromsystems Saliva Controls are intended to monitor the accuracy and precision of each analytical sequence and are available in two different concentration levels. The lyophilized controls are based on human saliva. After reconstitution, they are handled in the same manner as a patient sample and are analyzed under routine conditions analogous to the respective test procedure.

Sample Concentrator
Sample Concentrator for 96 Well Plates

The Chromsystems Sample Concentrator for 96 Well Plates accelerates the concentration of large sample numbers in mere minutes as compared to traditional methods which normally take hours. The light and compact unit for easy use in fume cupboards ensures fast evaporation of solvents and is ideal for clinical diagnostic purposes, such as Chromsystems MassChrom® Steroids assays.

Valve Actuator
CLC 230

The CLC 230 valve actuator is suitable as a switching valve for HPLC and LC-MS/MS and is available with an additional column switching valve for up to 6 columns. The CLC 230 valve actuator is ideal for online sample preparation.

Hemoglobin Variants Assay
Hemoglobin Variants – HPLC

The Chromsystems assay for the analysis of hemoglobin variants can determine the most common variants HbA1c, HbA2, HbC, HbD, HbE, HbF, and HbS within 9 minutes. A column material specially designed for this specific separation process also allows a stable separation of HbA2 from HbD and HbE even with aged columns. This helps to eliminate false quantifications and qualifications.

HPLC Column Thermostat Chromsystem
CLC 360

The CLC 360 HPLC Column Thermostat Chromsystem features a temperature controller for stable column temperatures along with an active heating/cooling system and Peltier technology. It also features a highly sensitive leak sensor that detects vapors of organic solvents along with overheat protection.

Drugs of Abuse Testing
MassTox Drugs of Abuse Testing

MassTox Drugs of Abuse Testing is an LC-MS/MS-based assay that helps to increase the speed of analysis and eliminates the need for developing and maintaining in-house methods or specific QC materials. The test is available with reaction vials or 96 well plates and allows the target screening of 108 drugs and metabolites while the confirmatory analysis can also be performed within the same run.

Neuroleptics Analysis Test
Parameter Set Neuroleptics 1/EXTENDED - LC-MS/MS

This assay enables the quantitative determination of aripiprazole, dehydroaripiprazole, clozapine, desmethylclozapine, haloperidol, quetiapine, norquetiapine, risperidone and 9-OH-risperidone in human serum or plasma samples as well as olanzapine and N-desmethylolanzapine in human EDTA plasma samples via liquid chromatography mass spectrometry (LC-MS/MS). It is intended as a therapeutic drug monitoring test, medically indicated for patients treated with one or more of the neuroleptic drugs listed above.

Quantitative Amino Acid Analysis Assay
MassChrom® Amino Acid Analysis in Urine with Reaction Vials - LC-MS/MS

This assay enables the quantitative determination of 53 amino acids and metabolites in urine including the parameter creatinine, so that the results can be directly related to the creatinine value without further analysis. It is intended to be used for patients with suspected metabolic diseases in whom the urinary amino acid and metabolic product levels are of clinical importance.

Immunosuppressant Kit
MassTox® Immunosuppressants in Whole Blood – LC-MS/MS

This assay allows the quantitative determination of cyclosporin A, everolimus, sirolimus (rapamycin), and tacrolimus (FK-506) in human EDTA whole blood samples via liquid chromatography-mass spectrometry (LC-MS/MS). It is intended as a therapeutic drug monitoring test for patients treated with one or several immunosuppressants named above.

Newborn Screening Assay
MassChrom Amino Acids and Acylcarnitines from Dried Blood

This Chromsystems assay allows for the fast determination of amino acids and acylcarnitines from dried blood spot samples as part of the newborn screening for amino acid and fatty acid metabolic disorders using tandem mass spectrometry. Sample preparation is based on the effective extraction of the analytes from the blood spot with subsequent derivatization.

Free Metanephrine Assay
MassChrom Free Metanephrines in Plasma with 96 SPE Well Plate

This assay allows for the quantitative determination of free metanephrine, free normetanephrine and free 3-methoxytyramine in human plasma samples by LC-MS/MS. The assay can be employed as an aid to diagnose and monitor suspected pheochromocytoma or paraganglioma. Furthermore, the assay is an aid to diagnosing and monitoring suspected neuroblastoma.

Porphyrins Urine Test
Porphyrins in Urine – HPLC

This assay allows for the quantitative determination of uroporphyrin, heptacarboxyporphyrin, hexacarboxyporphyrin, pentacarboxyporphyrin, coproporphyrin I and coproporphyrin III in human urine samples. It is intended to be used primarily as an aid to diagnosis of suspected acute intermittent porphyria, porphyria variegata, aminolevulinic acid dehydratase deficiency porphyria, hereditary coproporphyria, porphyria cutanea tarda or congenital erythropoietic porphyria and/or for their differential diagnosis.

Homocysteine Test
Homocysteine in Serum/Plasma – HPLC

This Chromsystems assay allows for the simple and reliable determination of total homocysteine in serum/plasma. Sample preparation is simply a reduction step for releasing homocysteine from its protein binding, followed by precipitation and subsequent precolumn derivatization. Chromatographic separation is performed on an isocratic HPLC system with fluorescence detection. The optimized reagents ensure the accurate and reliable quantification of total homocysteine for all blood collection systems within a brief analysis period of less than six minutes.

Chromsystem
Q-CLC 340

The Q-CLC 340 is an HPLC pump chromsystem with high flow rate consistency, low pulsation and a smaller volume vacuum degasser, requiring only 500 μl. Its pump head drive is permanently lubricated as well as accessible, while its reliable flow with all common mobile phases makes it ideally suited for routine clinical diagnostic use.

Chromsystem
CLC 100

The CLC 100 is an electrochemical detector chromsystem for the selective detection of oxidisable and reducible substances in medical diagnostics and pharmacology. Complete with flow cell and accessories, it offers a short equilibration time and is suitable for narrow-bore columns.