The EUROPattern Microscope automates immunofluorescence microscopy, including slide transport, image recording and archiving and interpretation of the immunofluorescence images. The high speed of the system and the minimization of manual handling enable the EUROPattern Microscope to be employed for standardized IFA diagnostics even at the highest of throughput requirements. The EUROPattern Microscope system consists of a fully automated microscope with a slide magazine (500 substrate fields per loading) together with sophisticated software. The EUROPattern Classifier, a module of EUROLabOffice 4.0, provides positive/negative classification for many substrates, as well as pattern recognition for ANA, ANCA, and further applications.