The Allplex SARS-CoV-2 Master Assay is intended for the full screening for SARS-CoV-2 and variants, including the five notable mutations in the S gene. It can be used alone or expanded to syndromic test with respiratory essential panel for common respiratory infections, including influenza A and B, metapneumovirus, parainfluenza virus 1/2/3/4, adenovirus, rhinovirus A/B/C and respiratory syncytial virus A/B, to provide more insights for diagnosis of symptomatic patients, especially with the emerging SARS-CoV-2 variants.